Jakavi® (Ruxolitinib)

Jakavi® (Ruxolitinib) Ruxolitinib 5 mg and Ruxolitinib 10 mg and Ruxolitinib 15 mg and Ruxolitinib 20 mg tablets by Novartis. Genuine stock supplied in bulk/wholesale quantities to hospitals and pharmacies across India by A.K. Pharma, a licensed pharmaceutical distributor in Delhi.

Additional information

Composition

Ruxolitinib 5 mg / Ruxolitinib 10 mg / Ruxolitinib 15 mg / Ruxolitinib 20 mg

Manufacturer

Novartis

Country

Switzerland

Pack size

Ruxolitinib 5 mg: 56 tablets (as shown on the carton); Ruxolitinib 10 mg: Please confirm current pack; Ruxolitinib 15 mg: Please confirm current pack; Ruxolitinib 20 mg: Please confirm current pack

Storage

Store in original pack as per carton instructions

Prescription medicine

Supplied only against a valid prescription from a registered medical practitioner.

100% genuine

Sourced from authorised channels

Cold-chain delivery

Temperature-controlled packing

Pan-India delivery

Hospitals, clinics, pharmacies

Licensed distributor

Delhi drug licence holder

Product information

Jakavi® (Ruxolitinib) Ruxolitinib 5 mg and Ruxolitinib 10 mg and Ruxolitinib 15 mg and Ruxolitinib 20 mg Tablets — JAK1/JAK2 Kinase Inhibitor: A Sourcing Guide for Hospitals and Oncology Pharmacies

Jakavi® is a brand of ruxolitinib tablets, a Janus kinase (JAK) inhibitor, marketed by Novartis. According to the US prescribing information for the same active ingredient (Jakafi®, Incyte), ruxolitinib is indicated for intermediate or high-risk myelofibrosis, polycythaemia vera in adults with an inadequate response to or intolerance of hydroxyurea, and steroid-refractory acute and chronic graft-versus-host disease in defined patients. Indications for Jakavi in India and elsewhere are defined by its approved pack insert and each regulator. The decision to prescribe ruxolitinib, including patient selection, dose and monitoring, rests entirely with the treating physician. This page provides sourcing and procurement information for hospitals and pharmacies, not clinical or treatment guidance.

As both a trusted medicine distributor in Delhi and a licensed pharmaceutical distributor in Delhi, A.K. Pharma supplies genuine Jakavi® (ruxolitinib) Ruxolitinib 5 mg and Ruxolitinib 10 mg and Ruxolitinib 15 mg and Ruxolitinib 20 mg tablets to hospitals, oncology centres and pharmacies across India. Buyers comparing pharmaceutical distribution companies and wholesale pharmaceutical distributors can also browse our full product range and the cancer medicines category. Supply is in bulk/wholesale quantities only.


What is Jakavi (Ruxolitinib)?

Jakavi contains ruxolitinib, an oral kinase inhibitor. The carton shown is the Novartis Jakavi 5 mg pack of 56 tablets; Jakavi is also supplied in higher strengths.

How it works, according to the label: The reference label describes ruxolitinib as an inhibitor of Janus-associated kinases JAK1 and JAK2, which are involved in signalling of cytokines and growth factors important for blood cell formation and immune function.


Indications as Listed in the Reference Label

The current US prescribing information for Jakafi® (ruxolitinib; same active ingredient) (DailyMed) lists the following. Indications in India may differ and are defined by the Indian regulator and the Jakavi pack insert.

  • Intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythaemia vera myelofibrosis and post-essential thrombocythaemia myelofibrosis, in adults
  • Polycythaemia vera in adults who have had an inadequate response to or are intolerant of hydroxyurea
  • Steroid-refractory acute graft-versus-host disease in adult and paediatric patients 12 years and older
  • Chronic graft-versus-host disease after failure of one or two lines of systemic therapy in adult and paediatric patients 12 years and older

Clinical Studies and Evidence

The studies below are summarised as published; they describe the evidence for ruxolitinib and are not a recommendation for any patient.

  • COMFORT-I (Verstovsek et al., New England Journal of Medicine, 2012) was a double-blind, placebo-controlled trial of ruxolitinib in myelofibrosis. Read the publication.
  • COMFORT-II (Harrison et al., New England Journal of Medicine, 2012) compared ruxolitinib with best available therapy in myelofibrosis. Read the publication.

Available Strengths and Packs

Strength Dosage form Pack size (as shown on the carton)
Ruxolitinib 5 mg Tablets (oral) 56 tablets (as shown on the carton)
Ruxolitinib 10 mg Tablets (oral) Please confirm current pack
Ruxolitinib 15 mg Tablets (oral) Please confirm current pack
Ruxolitinib 20 mg Tablets (oral) Please confirm current pack

Please confirm the current pack and batch with us before ordering. Dose and regimen must be determined and followed exactly as directed by the treating physician and the approved prescribing information.


Key Benefits for Procurement

  • Genuine, sealed original-pack stock sourced through authorised channels
  • Multiple strengths of one brand available from a single source
  • Batch and expiry details provided on request
  • Careful handling and storage of stock before dispatch
  • Documentation support for hospital purchase departments

Who Is This Page For?

This page is written for hospital pharmacists, haematology and oncology department buyers, and pharmacies that source specialty oral products. Ruxolitinib is prescribed and supervised by a physician, as described in the prescribing information.


Possible Side Effects Reported in the Label

The Jakafi label reports that, in myelofibrosis and polycythaemia vera, the most common haematologic adverse reactions (more than 20%) are thrombocytopenia and anaemia, and the most common non-haematologic reactions (15% or more) are bruising, dizziness, headache and diarrhoea. Warnings listed include thrombocytopenia, anaemia and neutropenia, risk of infection, symptom exacerbation after interruption or discontinuation, non-melanoma skin cancer and lipid elevations. This list is not complete; the full prescribing information governs.


Precautions

  • The label lists no contraindications but describes warnings including cytopenias, serious infections and non-melanoma skin cancer.
  • The label directs monitoring of blood counts before and during treatment, as determined by the treating physician.
  • The label describes symptom exacerbation after interruption or discontinuation of therapy.

All use should follow the approved prescribing information and the instructions of the treating physician.


Storage and Handling

Please follow the storage instructions printed on the Jakavi carton and leaflet. For reference, the US label for Jakafi describes storage at 20°C to 25°C in a tight container, protected from light.


Manufacturer Information

Jakavi is marketed by Novartis. A.K. Pharma is a licensed distributor and does not manufacture the product. As one of the pharmaceutical distributors serving Indian hospitals, we source Jakavi through authorised channels and supply it with pack and batch details. Buyers comparing a pharmaceutical wholesale distributors list or a pharma distribution company can verify our credentials on the About Us page.


Related Medicines


Frequently Asked Questions

Is Jakavi available in India?
A.K. Pharma supplies Jakavi (ruxolitinib) Ruxolitinib 5 mg and Ruxolitinib 10 mg and Ruxolitinib 15 mg and Ruxolitinib 20 mg tablets to hospitals and pharmacies in India. Contact us for current availability.

What does Jakavi contain?
Ruxolitinib, a JAK1/JAK2 inhibitor, in 5, 10, 15 and 20 mg tablets.

Can I order a single pack?
A.K. Pharma is a distributor and supplies bulk/wholesale quantities only, not one or two pieces.

How should Jakavi be stored?
As printed on the carton and leaflet, in the original pack.

Does A.K. Pharma advise on dosing or suitability?
No. Treatment decisions, including dosing, rest solely with the treating physician and the approved prescribing information.

How do I request a quote?
Call or WhatsApp us, or use the contact details below.


Why Order from A.K. Pharma

  • Licensed pharmaceutical distributor in Delhi with 25+ years in specialty medicines
  • Genuine, original-pack stock
  • Bulk/wholesale supply to hospitals, oncology centres and pharmacies
  • Batch and expiry details on request
  • Dedicated team for hospital procurement queries

Sources and Further Reading


Contact A.K. Pharma for Jakavi Supply

📍 E-2/257A, 2nd Floor, Shastri Nagar, New Delhi 110052
📞 011 4172 6999
📱 WhatsApp: +91 9810034827
🌐 akpharma.in


Disclaimer: This page is intended for informational and sourcing/procurement purposes only and does not constitute medical or clinical advice. A.K. Pharma is a licensed medicine distributor, not a healthcare provider, and does not provide clinical guidance. All treatment decisions, including drug selection and dosing, rest solely with the treating physician and should follow the approved prescribing information.

Hi! 👋 Looking for a medicine? I can help you find it.

Quote Request Form


Quote Request Form