Opdivo® (Nivolumab)

Opdivo® (Nivolumab) Nivolumab 100 mg/10 mL (10 mg/mL) injection for intravenous infusion by Bristol-Myers Squibb. Genuine stock supplied in bulk/wholesale quantities to hospitals and pharmacies across India by A.K. Pharma, a licensed pharmaceutical distributor in Delhi.

Additional information

Composition

Nivolumab 100 mg/10 mL (10 mg/mL)

Manufacturer

Bristol-Myers Squibb

Country

USA

Pack size

Nivolumab 100 mg/10 mL (10 mg/mL): 1 vial / carton

Storage

As per carton and leaflet; original pack

Prescription medicine

Supplied only against a valid prescription from a registered medical practitioner.

100% genuine

Sourced from authorised channels

Cold-chain delivery

Temperature-controlled packing

Pan-India delivery

Hospitals, clinics, pharmacies

Licensed distributor

Delhi drug licence holder

Product information

Opdivo® (Nivolumab) Nivolumab 100 mg/10 mL (10 mg/mL) Injection for Intravenous Infusion — PD-1 Blocking Antibody: A Sourcing Guide for Hospitals and Oncology Pharmacies

Opdivo® is a brand of nivolumab, a programmed death receptor-1 (PD-1) blocking monoclonal antibody, marketed by Bristol-Myers Squibb. According to the current US prescribing information, Opdivo is indicated, as a single agent or in combination with other therapies, for a range of cancers including melanoma, non-small cell lung cancer, malignant pleural mesothelioma, renal cell carcinoma, classical Hodgkin lymphoma, squamous cell carcinoma of the head and neck, urothelial carcinoma, colorectal cancer, hepatocellular carcinoma, and esophageal and gastric cancers. Indications for Opdivo in India are defined by its approved pack insert and the Indian regulator. The decision to prescribe nivolumab, including patient selection, dose and monitoring, rests entirely with the treating physician. This page provides sourcing and procurement information for hospitals and pharmacies, not clinical or treatment guidance.

As both a trusted medicine distributor in Delhi and a licensed pharmaceutical distributor in Delhi, A.K. Pharma supplies genuine Opdivo® (nivolumab) Nivolumab 100 mg/10 mL (10 mg/mL) injection for intravenous infusion to hospitals, oncology centres and pharmacies across India. Buyers comparing pharmaceutical distribution companies and wholesale pharmaceutical distributors can also browse our full product range and the cancer medicines category. Supply is in bulk/wholesale quantities only.


What is Opdivo (Nivolumab)?

Opdivo contains nivolumab, a human monoclonal antibody supplied as a single-dose vial for intravenous infusion. The Opdivo pack shown on this page states 100 mg/10 mL (10 mg/mL).

How it works, according to the label: The reference label describes nivolumab as a PD-1 blocking antibody. The label warns that it can cause immune-mediated adverse reactions in any organ system.


Indications as Listed in the Reference Label

The current US prescribing information for OPDIVO® (nivolumab) injection (DailyMed) lists the following. Indications in India may differ and are defined by the Indian regulator and the Opdivo pack insert.

  • Melanoma: unresectable or metastatic melanoma (single agent or with ipilimumab) and adjuvant treatment of resected melanoma
  • Non-small cell lung cancer: neoadjuvant and perioperative use with chemotherapy, and first-line and previously treated metastatic disease, as specified in the label
  • Malignant pleural mesothelioma, advanced renal cell carcinoma and classical Hodgkin lymphoma, in the settings described in the label
  • Squamous cell carcinoma of the head and neck, urothelial carcinoma and MSI-H/dMMR colorectal cancer, in the settings described in the label
  • Hepatocellular carcinoma, esophageal cancer and gastric cancer, in the settings described in the label
  • The label lists no contraindications

Clinical Studies and Evidence

The Opdivo label summarises its Clinical Studies by indication. In previously untreated melanoma, the CheckMate 067 trial compared nivolumab plus ipilimumab, nivolumab alone and ipilimumab alone; it was published by Larkin et al. in the New England Journal of Medicine in 2015. Full results for each indication are in the DailyMed prescribing information. Evidence is cited for information only and is not a recommendation for any patient; the approved prescribing information governs.


Available Presentation

Strength Dosage form Pack size (as shown on the carton)
Nivolumab 100 mg/10 mL (10 mg/mL) Injection for intravenous infusion (single-dose vial) 1 vial / carton

Please confirm the current pack and batch with us before ordering. Dose and regimen must be determined and followed exactly as directed by the treating physician and the approved prescribing information.


Key Benefits for Procurement

  • Genuine, sealed original-pack stock sourced through authorised channels
  • Original manufacturer packaging with batch and expiry details
  • Batch and expiry details provided on request
  • Careful handling and storage of stock before dispatch
  • Documentation support for hospital purchase departments

Who Is This Page For?

This page is written for hospital pharmacists, oncology department buyers and pharmacies that source biologic oncology products. Nivolumab is prescribed and supervised by a physician, as described in the prescribing information.


Possible Side Effects Reported in the Label

The Opdivo label lists, as most common adverse reactions (20% or more) as a single agent, fatigue, rash, musculoskeletal pain, pruritus, diarrhea, nausea, asthenia, cough, dyspnea, constipation, decreased appetite and others. Its warnings cover immune-mediated adverse reactions, including pneumonitis, colitis, hepatitis, endocrinopathies, dermatologic reactions and nephritis, which may be severe or fatal, as well as infusion-related reactions and embryo-fetal toxicity. This list is not complete; the full prescribing information governs.


Precautions

  • The label lists no contraindications.
  • The label warns of immune-mediated adverse reactions that may require corticosteroid treatment and withholding of therapy, as determined by the treating physician.
  • The label describes monitoring for immune-mediated reactions and for infusion-related reactions during treatment.
  • The label describes embryo-fetal toxicity and advises effective contraception, as determined by the treating physician.
  • All use should follow the approved prescribing information and the instructions of the treating physician.

All use should follow the approved prescribing information and the instructions of the treating physician.


Storage and Handling

Please follow the storage instructions printed on the Opdivo carton and leaflet. For reference, the US label describes refrigeration at 2°C to 8°C, protected from light in the original package, and states not to freeze or shake. Keep out of reach of children.


Manufacturer Information

Opdivo is marketed by Bristol-Myers Squibb. A.K. Pharma is a licensed distributor and does not manufacture the product. As one of the pharmaceutical distributors serving Indian hospitals, we source Opdivo through authorised channels and supply it with pack and batch details. Buyers comparing a pharmaceutical wholesale distributors list or a pharma distribution company can verify our credentials on the About Us page.


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Frequently Asked Questions

Is Opdivo available in India?
A.K. Pharma supplies Opdivo (nivolumab) Nivolumab 100 mg/10 mL (10 mg/mL) injection for intravenous infusion to hospitals and pharmacies in India. Contact us for current availability.

What does Opdivo contain?
Nivolumab, a PD-1 blocking monoclonal antibody, as a single-dose vial for intravenous infusion.

Can I order a single pack?
A.K. Pharma is a distributor and supplies bulk/wholesale quantities only, not one or two pieces.

How should Opdivo be stored?
As printed on the carton. The US label describes refrigeration at 2°C to 8°C in the original package, protected from light, not frozen or shaken.

Does A.K. Pharma advise on dosing or suitability?
No. Treatment decisions, including dosing, rest solely with the treating physician and the approved prescribing information.

How do I request a quote?
Call or WhatsApp us, or use the contact details below.


Why Order from A.K. Pharma

  • Licensed pharmaceutical distributor in Delhi with 25+ years in specialty medicines
  • Genuine, original-pack stock
  • Bulk/wholesale supply to hospitals, oncology centres and pharmacies
  • Batch and expiry details on request
  • Dedicated team for hospital procurement queries

Sources and Further Reading


Contact A.K. Pharma for Opdivo Supply

📍 E-2/257A, 2nd Floor, Shastri Nagar, New Delhi 110052
📞 011 4172 6999
📱 WhatsApp: +91 9810034827
🌐 akpharma.in


Disclaimer: This page is intended for informational and sourcing/procurement purposes only and does not constitute medical or clinical advice. A.K. Pharma is a licensed medicine distributor, not a healthcare provider, and does not provide clinical guidance. All treatment decisions, including drug selection and dosing, rest solely with the treating physician and should follow the approved prescribing information.

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