Kombiglyze XR® (Saxagliptin + Metformin)

Kombiglyze XR® (Saxagliptin + Metformin) Saxagliptin 5 mg + Metformin HCl 500 mg and Saxagliptin 5 mg + Metformin HCl 1000 mg extended-release tablets by AstraZeneca. Genuine stock supplied in bulk/wholesale quantities to hospitals and pharmacies across India by A.K. Pharma, a licensed pharmaceutical distributor in Delhi.

Additional information

Composition

Saxagliptin 5 mg + Metformin HCl 500 mg / Saxagliptin 5 mg + Metformin HCl 1000 mg

Manufacturer

AstraZeneca

Country

India

Pack size

Saxagliptin 5 mg + Metformin HCl 500 mg: 4 x 7 tablets (as shown on the carton); Saxagliptin 5 mg + Metformin HCl 1000 mg: 4 x 7 tablets (as shown on the carton)

Storage

Store as per the carton; the US reference label describes 20°C to 25°C.

Prescription medicine

Supplied only against a valid prescription from a registered medical practitioner.

100% genuine

Sourced from authorised channels

Cold-chain delivery

Temperature-controlled packing

Pan-India delivery

Hospitals, clinics, pharmacies

Licensed distributor

Delhi drug licence holder

Product information

Kombiglyze XR® (Saxagliptin + Metformin) Saxagliptin 5 mg + Metformin HCl 500 mg and Saxagliptin 5 mg + Metformin HCl 1000 mg Extended-Release Tablets — DPP-4 Inhibitor and Biguanide Extended-Release Tablets: A Sourcing Guide for Hospitals and Pharmacies

Kombiglyze® XR is a brand of saxagliptin and metformin hydrochloride extended-release tablets (5 mg/500 mg and 5 mg/1000 mg) from AstraZeneca, shown on the cartons as packs of 4 x 7 tablets. According to the current US prescribing information for saxagliptin and metformin hydrochloride extended-release tablets, the combination is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Indications in India are defined by its approved pack insert and the Indian regulator. The decision to prescribe saxagliptin + metformin, including patient selection, dose and monitoring, rests entirely with the treating physician. This page provides sourcing and procurement information for hospitals and pharmacies, not clinical or treatment guidance.

As both a trusted medicine distributor in Delhi and a licensed pharmaceutical distributor in Delhi, A.K. Pharma supplies genuine Kombiglyze XR® (saxagliptin + metformin) Saxagliptin 5 mg + Metformin HCl 500 mg and Saxagliptin 5 mg + Metformin HCl 1000 mg extended-release tablets to hospitals and pharmacies across India. Buyers comparing pharmaceutical distribution companies and wholesale pharmaceutical distributors can also browse our full product range and the diabetes medicines category. Supply is in bulk/wholesale quantities only.


What is Kombiglyze XR (Saxagliptin + Metformin)?

Kombiglyze XR contains saxagliptin and metformin hydrochloride in extended-release tablets, in the strengths listed below.

How it works, according to the label: The reference label describes the combination of saxagliptin, a DPP4 inhibitor, and metformin hydrochloride, a biguanide, in an extended-release tablet.


Indications as Listed in the Reference Label

The current US prescribing information for saxagliptin and metformin hydrochloride extended-release tablets (DailyMed) lists the following. Indications in India may differ and are defined by the Indian regulator and the Kombiglyze XR pack insert.

  • Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
  • Limitation of use: not recommended for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis
  • Further details are described in the label, as specified in the label

Clinical Studies and Evidence

The reference label summarises its Clinical Studies in type 2 diabetes, and the cardiovascular outcomes of the saxagliptin component were studied in SAVOR-TIMI 53, published by Scirica et al. in the New England Journal of Medicine in 2013. Evidence is cited for information only and is not a recommendation for any patient; the approved prescribing information governs.


Available Strengths and Packs

Strength Dosage form Pack size (as shown on the carton)
Saxagliptin 5 mg + Metformin HCl 500 mg Extended-release tablets 4 x 7 tablets (as shown on the carton)
Saxagliptin 5 mg + Metformin HCl 1000 mg Extended-release tablets 4 x 7 tablets (as shown on the carton)

Please confirm the current pack and batch with us before ordering. Dose and regimen must be determined and followed exactly as directed by the treating physician and the approved prescribing information.


Key Benefits for Procurement

  • Genuine, sealed original-pack stock sourced through authorised channels
  • Multiple strengths of one brand available from a single source
  • Batch and expiry details provided on request
  • Careful handling and storage of stock before dispatch
  • Documentation support for hospital purchase departments

Who Is This Page For?

This page is written for hospital pharmacists, endocrinology and diabetology department buyers and pharmacies that source antidiabetic products. The product is prescribed and supervised by a physician, as described in the prescribing information.


Possible Side Effects Reported in the Label

The reference label carries a boxed warning for lactic acidosis. It lists diarrhoea and nausea/vomiting among the most common adverse reactions of the metformin extended-release component (over 5%). This list is not complete; the full prescribing information governs.


Precautions

  • The reference label carries a boxed warning on metformin-associated lactic acidosis, which can result in death.
  • The label describes warnings including pancreatitis, heart failure, hypersensitivity and hypoglycaemia.
  • The label states that it is not recommended for type 1 diabetes mellitus or diabetic ketoacidosis.
  • Any decision on use and dosing is made by the treating physician in line with the approved prescribing information.

All use should follow the approved prescribing information and the instructions of the treating physician.


Storage and Handling

Please follow the storage instructions printed on the Kombiglyze XR carton and strip. For reference, the US label describes storage at 20°C to 25°C. Keep out of reach of children.


Manufacturer Information

Kombiglyze XR is marketed by AstraZeneca. A.K. Pharma is a licensed distributor and does not manufacture the product. As one of the pharmaceutical distributors serving Indian hospitals, we source Kombiglyze XR through authorised channels and supply it with pack and batch details. Buyers comparing a pharmaceutical wholesale distributors list or a pharma distribution company can verify our credentials on the About Us page.


Related Medicines


Frequently Asked Questions

Is Kombiglyze XR available in India?
A.K. Pharma supplies Kombiglyze XR (saxagliptin + metformin) Saxagliptin 5 mg + Metformin HCl 500 mg and Saxagliptin 5 mg + Metformin HCl 1000 mg extended-release tablets to hospitals and pharmacies in India. Contact us for current availability.

What does Kombiglyze XR contain?
Saxagliptin (a DPP-4 inhibitor) with metformin hydrochloride, as extended-release tablets.

Can I order a single pack?
A.K. Pharma is a distributor and supplies bulk/wholesale quantities only, not one or two pieces.

How should Kombiglyze XR be stored?
Follow the carton and strip; the US reference label describes 20°C to 25°C.

Does A.K. Pharma advise on dosing or suitability?
No. Treatment decisions, including dosing, rest solely with the treating physician and the approved prescribing information.

How do I request a quote?
Call or WhatsApp us, or use the contact details below.


Why Order from A.K. Pharma

  • Licensed pharmaceutical distributor in Delhi with 25+ years in specialty medicines
  • Genuine, original-pack stock
  • Bulk/wholesale supply to hospitals and pharmacies
  • Batch and expiry details on request
  • Dedicated team for hospital procurement queries

Sources and Further Reading


Contact A.K. Pharma for Kombiglyze XR Supply

📍 E-2/257A, 2nd Floor, Shastri Nagar, New Delhi 110052
📞 011 4172 6999
📱 WhatsApp: +91 9810034827
🌐 akpharma.in


Disclaimer: This page is intended for informational and sourcing/procurement purposes only and does not constitute medical or clinical advice. A.K. Pharma is a licensed medicine distributor, not a healthcare provider, and does not provide clinical guidance. All treatment decisions, including drug selection and dosing, rest solely with the treating physician and should follow the approved prescribing information.

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