Bosentas® (Bosentan)

Bosentas® (Bosentan) Bosentan 125 mg tablets by Cipla. Genuine stock supplied in bulk/wholesale quantities to hospitals and pharmacies across India by A.K. Pharma, a licensed pharmaceutical distributor in Delhi.

Additional information

Composition

Bosentan 125 mg

Manufacturer

Cipla

Country

India

Pack size

Bosentan 125 mg: 10 tablets (as listed)

Storage

Store below 25°C in a cool, dry place as printed on the strip.

Prescription medicine

Supplied only against a valid prescription from a registered medical practitioner.

100% genuine

Sourced from authorised channels

Cold-chain delivery

Temperature-controlled packing

Pan-India delivery

Hospitals, clinics, pharmacies

Licensed distributor

Delhi drug licence holder

Product information

Bosentas® (Bosentan) Bosentan 125 mg Tablets — Endothelin Receptor Antagonist Tablets IP: A Sourcing Guide for Hospitals and Pharmacies

Bosentas® is a brand of bosentan tablets IP 125 mg marketed in India by Cipla, shown on the strip as film-coated tablets in a pack of 10. According to the current US prescribing information for the reference product Tracleer, bosentan is an endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension (PAH, WHO Group 1) in adults and in pediatric patients aged 3 years and older with idiopathic or congenital PAH. Indications in India are defined by its approved pack insert and the Indian regulator. The decision to prescribe bosentan, including patient selection, dose and monitoring, rests entirely with the treating physician. This page provides sourcing and procurement information for hospitals and pharmacies, not clinical or treatment guidance.

As both a trusted medicine distributor in Delhi and a licensed pharmaceutical distributor in Delhi, A.K. Pharma supplies genuine Bosentas® (bosentan) Bosentan 125 mg tablets to hospitals and pharmacies across India. Buyers comparing pharmaceutical distribution companies and wholesale pharmaceutical distributors can also browse our full product range and the heart medicines category. Supply is in bulk/wholesale quantities only.


What is Bosentas (Bosentan)?

Bosentas contains bosentan (as bosentan monohydrate) 125 mg in film-coated tablets, supplied in the pack size listed below.

How it works, according to the label: The reference label describes bosentan as an endothelin receptor antagonist; endothelin-1 is a vasoconstrictor and mitogen implicated in pulmonary arterial hypertension.


Indications as Listed in the Reference Label

The current US prescribing information for TRACLEER® (bosentan) tablets (DailyMed) lists the following. Indications in India may differ and are defined by the Indian regulator and the Bosentas pack insert.

  • Treatment of pulmonary arterial hypertension (WHO Group 1) in adults, to improve exercise ability and to decrease clinical worsening
  • Treatment of idiopathic or congenital pulmonary arterial hypertension in pediatric patients aged 3 years and older, to improve pulmonary vascular resistance
  • Studies establishing effectiveness are described in the label, as specified in the label

Clinical Studies and Evidence

The reference label summarises its Clinical Studies in pulmonary arterial hypertension. The placebo-controlled study of bosentan therapy in pulmonary arterial hypertension was published by Rubin et al. in the New England Journal of Medicine in 2002. Evidence is cited for information only and is not a recommendation for any patient; the approved prescribing information governs.


Available Presentation

Strength Dosage form Pack size (as shown on the carton)
Bosentan 125 mg Film-coated tablets IP 10 tablets (as listed)

Please confirm the current pack and batch with us before ordering. Dose and regimen must be determined and followed exactly as directed by the treating physician and the approved prescribing information.


Key Benefits for Procurement

  • Genuine, sealed original-pack stock sourced through authorised channels
  • Original manufacturer packaging with batch and expiry details
  • Batch and expiry details provided on request
  • Careful handling and storage of stock before dispatch
  • Documentation support for hospital purchase departments

Who Is This Page For?

This page is written for hospital pharmacists, cardiology and pulmonology department buyers and pharmacies that source pulmonary hypertension products. Bosentan is prescribed and supervised by a specialist physician, as described in the prescribing information.


Possible Side Effects Reported in the Label

The reference label carries a boxed warning for hepatotoxicity and embryo-fetal toxicity and describes a restricted-access programme in the US. It describes headache, nasopharyngitis, flushing, abnormal liver function, oedema and anaemia among reported adverse reactions. This list is not complete; the full prescribing information governs.


Precautions

  • The reference label carries a boxed warning on hepatotoxicity and on embryo-fetal toxicity.
  • The label describes monitoring of liver aminotransferases and haemoglobin, as determined by the treating physician.
  • The label describes pregnancy testing and contraception requirements for females of reproductive potential.
  • Any decision on use, monitoring and dosing is made by the treating physician in line with the approved prescribing information.

All use should follow the approved prescribing information and the instructions of the treating physician.


Storage and Handling

Please follow the storage instructions printed on the Bosentas strip, which states storage below 25°C in a cool and dry place. For reference, the US Tracleer label describes 20°C to 25°C. Keep out of reach of children.


Manufacturer Information

Bosentas is marketed by Cipla. A.K. Pharma is a licensed distributor and does not manufacture the product. As one of the pharmaceutical distributors serving Indian hospitals, we source Bosentas through authorised channels and supply it with pack and batch details. Buyers comparing a pharmaceutical wholesale distributors list or a pharma distribution company can verify our credentials on the About Us page.


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Frequently Asked Questions

Is Bosentas available in India?
A.K. Pharma supplies Bosentas (bosentan) Bosentan 125 mg tablets to hospitals and pharmacies in India. Contact us for current availability.

What does Bosentas contain?
Bosentan, an endothelin receptor antagonist, 125 mg in film-coated tablets.

Can I order a single pack?
A.K. Pharma is a distributor and supplies bulk/wholesale quantities only, not one or two pieces.

How should Bosentas be stored?
Follow the strip, which states below 25°C in a cool, dry place.

Does A.K. Pharma advise on dosing or suitability?
No. Treatment decisions, including dosing, rest solely with the treating physician and the approved prescribing information.

How do I request a quote?
Call or WhatsApp us, or use the contact details below.


Why Order from A.K. Pharma

  • Licensed pharmaceutical distributor in Delhi with 25+ years in specialty medicines
  • Genuine, original-pack stock
  • Bulk/wholesale supply to hospitals and pharmacies
  • Batch and expiry details on request
  • Dedicated team for hospital procurement queries

Sources and Further Reading


Contact A.K. Pharma for Bosentas Supply

📍 E-2/257A, 2nd Floor, Shastri Nagar, New Delhi 110052
📞 011 4172 6999
📱 WhatsApp: +91 9810034827
🌐 akpharma.in


Disclaimer: This page is intended for informational and sourcing/procurement purposes only and does not constitute medical or clinical advice. A.K. Pharma is a licensed medicine distributor, not a healthcare provider, and does not provide clinical guidance. All treatment decisions, including drug selection and dosing, rest solely with the treating physician and should follow the approved prescribing information.

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