Actorise® (Darbepoetin Alfa)

Actorise® (Darbepoetin Alfa) Darbepoetin alfa 40 mcg/0.4 mL and Darbepoetin alfa 60 mcg and Darbepoetin alfa 200 mcg prefilled syringe by Cipla. Genuine stock supplied in bulk/wholesale quantities to hospitals and pharmacies across India by A.K. Pharma, a licensed pharmaceutical distributor in Delhi.

Additional information

Composition

Darbepoetin alfa 40 mcg/0.4 mL / Darbepoetin alfa 60 mcg / Darbepoetin alfa 200 mcg

Manufacturer

Cipla

Country

India

Pack size

Darbepoetin alfa 40 mcg/0.4 mL: 1 prefilled syringe / carton; Darbepoetin alfa 60 mcg: 1 prefilled syringe / carton; Darbepoetin alfa 200 mcg: 1 prefilled syringe / carton

Storage

Store as per carton and leaflet; original sealed pack

Prescription medicine

Supplied only against a valid prescription from a registered medical practitioner.

100% genuine

Sourced from authorised channels

Cold-chain delivery

Temperature-controlled packing

Pan-India delivery

Hospitals, clinics, pharmacies

Licensed distributor

Delhi drug licence holder

Product information

Actorise® (Darbepoetin Alfa) Darbepoetin alfa 40 mcg/0.4 mL and Darbepoetin alfa 60 mcg and Darbepoetin alfa 200 mcg Prefilled Syringe — Erythropoiesis-Stimulating Agent for Injection: A Sourcing Guide for Hospitals and Pharmacies

Actorise® is a brand of darbepoetin alfa injection in single-dose prefilled syringes, marketed by Cipla in 40 mcg, 60 mcg and 200 mcg presentations. According to the US prescribing information for darbepoetin alfa (Aranesp®), it is an erythropoiesis-stimulating agent (ESA) indicated for anemia due to chronic kidney disease and for anemia due to chemotherapy in patients with cancer. Use of Actorise in India is defined by its approved pack insert and the Indian regulator. The decision to prescribe darbepoetin alfa, including patient selection, dose and monitoring, rests entirely with the treating physician. This page provides sourcing and procurement information for hospitals and pharmacies, not clinical or treatment guidance.

As both a trusted medicine distributor in Delhi and a licensed pharmaceutical distributor in Delhi, A.K. Pharma supplies genuine Actorise® (darbepoetin alfa) Darbepoetin alfa 40 mcg/0.4 mL and Darbepoetin alfa 60 mcg and Darbepoetin alfa 200 mcg prefilled syringe to hospitals and pharmacies across India. Buyers comparing pharmaceutical distribution companies and wholesale pharmaceutical distributors can also browse our full product range and the blood medicines category. Supply is in bulk/wholesale quantities only.


What is Actorise (Darbepoetin Alfa)?

Actorise contains darbepoetin alfa, a recombinant protein that stimulates red blood cell production, supplied as a single-dose prefilled syringe for subcutaneous or intravenous use as described in the pack insert.

How it works, according to the label: The reference label describes darbepoetin alfa as an ESA that stimulates erythropoiesis through the same mechanism as endogenous erythropoietin.


Indications as Listed in the Reference Label

The current US prescribing information for ARANESP® (darbepoetin alfa) injection, the reference brand of the same molecule (DailyMed) lists the following. Indications in India may differ and are defined by the Indian regulator and the Actorise pack insert.

  • Treatment of anemia due to chronic kidney disease (CKD), in patients on dialysis and not on dialysis
  • Treatment of anemia due to the effect of concomitant myelosuppressive chemotherapy in patients with non-myeloid malignancies, as specified in the label
  • The label states that it has not been shown to improve quality of life, fatigue or well-being

Clinical Studies and Evidence

The reference label summarises its Clinical Studies in CKD and chemotherapy-related anemia. The TREAT trial of darbepoetin alfa in patients with type 2 diabetes and chronic kidney disease was published by Pfeffer et al. in the New England Journal of Medicine in 2009. Evidence is cited for information only and is not a recommendation for any patient; the approved prescribing information governs.


Available Strengths and Packs

Strength Dosage form Pack size (as shown on the carton)
Darbepoetin alfa 40 mcg/0.4 mL Solution for injection, single-dose prefilled syringe 1 prefilled syringe / carton
Darbepoetin alfa 60 mcg Solution for injection, single-dose prefilled syringe 1 prefilled syringe / carton
Darbepoetin alfa 200 mcg Solution for injection, single-dose prefilled syringe 1 prefilled syringe / carton

Please confirm the current pack and batch with us before ordering. Dose and regimen must be determined and followed exactly as directed by the treating physician and the approved prescribing information.


Key Benefits for Procurement

  • Genuine, sealed original-pack stock sourced through authorised channels
  • Multiple strengths of one brand available from a single source
  • Batch and expiry details provided on request
  • Careful handling and storage of stock before dispatch
  • Documentation support for hospital purchase departments

Who Is This Page For?

This page is written for hospital pharmacists, nephrology and oncology department buyers and pharmacies that source biologic products. Darbepoetin alfa is prescribed and supervised by a physician, as described in the prescribing information.


Possible Side Effects Reported in the Label

The Aranesp label lists, among its warnings, an increased risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence with ESAs, as well as hypertension, seizures, pure red cell aplasia and serious allergic reactions. This list is not complete; the full prescribing information governs.


Precautions

  • The reference label carries a boxed warning that ESAs increase the risk of death and serious cardiovascular and thromboembolic events, and may shorten survival or time to tumor progression in cancer.
  • The label advises using the lowest dose needed to reduce red blood cell transfusions, as determined by the treating physician.
  • The label describes evaluating iron status before and during treatment.
  • The label describes pure red cell aplasia and serious allergic reactions as warnings.

All use should follow the approved prescribing information and the instructions of the treating physician.


Storage and Handling

Please follow the storage instructions printed on the Actorise carton and syringe. For reference, the US Aranesp label describes refrigeration at 2°C to 8°C, protected from light, and states not to freeze or shake. Keep out of reach of children.


Manufacturer Information

Actorise is marketed by Cipla. A.K. Pharma is a licensed distributor and does not manufacture the product. As one of the pharmaceutical distributors serving Indian hospitals, we source Actorise through authorised channels and supply it with pack and batch details. Buyers comparing a pharmaceutical wholesale distributors list or a pharma distribution company can verify our credentials on the About Us page.


Related Medicines


Frequently Asked Questions

Is Actorise available in India?
A.K. Pharma supplies Actorise (darbepoetin alfa) Darbepoetin alfa 40 mcg/0.4 mL and Darbepoetin alfa 60 mcg and Darbepoetin alfa 200 mcg prefilled syringe to hospitals and pharmacies in India. Contact us for current availability.

What does Actorise contain?
Darbepoetin alfa, an ESA supplied as 40 mcg, 60 mcg and 200 mcg single-dose prefilled syringes.

Can I order a single pack?
A.K. Pharma is a distributor and supplies bulk/wholesale quantities only, not one or two pieces.

How should Actorise be stored?
Follow the carton; the US reference label describes 2°C to 8°C, protected from light, not frozen or shaken.

Does A.K. Pharma advise on dosing or suitability?
No. Treatment decisions, including dosing, rest solely with the treating physician and the approved prescribing information.

How do I request a quote?
Call or WhatsApp us, or use the contact details below.


Why Order from A.K. Pharma

  • Licensed pharmaceutical distributor in Delhi with 25+ years in specialty medicines
  • Genuine, original-pack stock
  • Bulk/wholesale supply to hospitals and pharmacies
  • Batch and expiry details on request
  • Dedicated team for hospital procurement queries

Sources and Further Reading


Contact A.K. Pharma for Actorise Supply

📍 E-2/257A, 2nd Floor, Shastri Nagar, New Delhi 110052
📞 011 4172 6999
📱 WhatsApp: +91 9810034827
🌐 akpharma.in


Disclaimer: This page is intended for informational and sourcing/procurement purposes only and does not constitute medical or clinical advice. A.K. Pharma is a licensed medicine distributor, not a healthcare provider, and does not provide clinical guidance. All treatment decisions, including drug selection and dosing, rest solely with the treating physician and should follow the approved prescribing information.

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