Denaxa® (Denosumab)

Denaxa® (Denosumab) Denosumab 60 mg/mL prefilled syringe by Abbott. Genuine stock supplied in bulk/wholesale quantities to hospitals and pharmacies across India by A.K. Pharma, a licensed pharmaceutical distributor in Delhi.

Additional information

Composition

Denosumab 60 mg/mL

Manufacturer

Abbott

Country

India

Pack size

Denosumab 60 mg/mL: 1 prefilled syringe / carton

Storage

Store as per carton and leaflet; original sealed pack

Prescription medicine

Supplied only against a valid prescription from a registered medical practitioner.

100% genuine

Sourced from authorised channels

Cold-chain delivery

Temperature-controlled packing

Pan-India delivery

Hospitals, clinics, pharmacies

Licensed distributor

Delhi drug licence holder

Product information

Denaxa® (Denosumab) Denosumab 60 mg/mL Prefilled Syringe — RANKL Inhibitor for Injection: A Sourcing Guide for Hospitals and Pharmacies

Denaxa® is a brand of denosumab 60 mg/mL injection supplied in a single-dose prefilled syringe, marketed in India by Abbott Healthcare Pvt Ltd and manufactured at Enzene Biosciences, Pune. According to the reference US prescribing information for denosumab 60 mg (Prolia®), this strength is a RANK ligand (RANKL) inhibitor indicated for osteoporosis in specified patient groups. Use of Denaxa in India is defined by its approved pack insert and the Indian regulator. The decision to prescribe denosumab, including patient selection, dose and monitoring, rests entirely with the treating physician. This page provides sourcing and procurement information for hospitals and pharmacies, not clinical or treatment guidance.

As both a trusted medicine distributor in Delhi and a licensed pharmaceutical distributor in Delhi, A.K. Pharma supplies genuine Denaxa® (denosumab) Denosumab 60 mg/mL prefilled syringe to hospitals and pharmacies across India. Buyers comparing pharmaceutical distribution companies and wholesale pharmaceutical distributors can also browse our full product range and the hormone medicines category. Supply is in bulk/wholesale quantities only.


What is Denaxa (Denosumab)?

Denaxa contains denosumab, a human monoclonal antibody, as a 60 mg/mL solution in a single-dose prefilled syringe for subcutaneous injection, administered by a healthcare professional as the reference label describes.

How it works, according to the label: The reference label describes denosumab as a monoclonal antibody that binds RANKL, a protein that drives osteoclast formation and activity, and so reduces bone resorption.


Indications as Listed in the Reference Label

The current US prescribing information for Prolia® (denosumab) injection, the reference brand of the same molecule and strength (DailyMed) lists the following. Indications in India may differ and are defined by the Indian regulator and the Denaxa pack insert.

  • Treatment of postmenopausal women with osteoporosis at high risk for fracture
  • Increase of bone mass in men with osteoporosis at high risk for fracture
  • Glucocorticoid-induced osteoporosis in men and women at high risk for fracture
  • Bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer, and in women receiving adjuvant aromatase inhibitor therapy for breast cancer

Clinical Studies and Evidence

The reference label summarises its Clinical Studies by indication. In postmenopausal women with osteoporosis, the FREEDOM trial compared denosumab with placebo and was published by Cummings et al. in the New England Journal of Medicine in 2009. Evidence is cited for information only and is not a recommendation for any patient; the approved prescribing information governs.


Available Presentation

Strength Dosage form Pack size (as shown on the carton)
Denosumab 60 mg/mL Solution for injection in single-dose prefilled syringe 1 prefilled syringe / carton

Please confirm the current pack and batch with us before ordering. Dose and regimen must be determined and followed exactly as directed by the treating physician and the approved prescribing information.


Key Benefits for Procurement

  • Genuine, sealed original-pack stock sourced through authorised channels
  • Original manufacturer packaging with batch and expiry details
  • Batch and expiry details provided on request
  • Careful handling and storage of stock before dispatch
  • Documentation support for hospital purchase departments

Who Is This Page For?

This page is written for hospital pharmacists, osteoporosis and oncology department buyers and pharmacies that source biologic products. Denosumab is prescribed and supervised by a physician, as described in the prescribing information.


Possible Side Effects Reported in the Label

The Prolia label lists, as most common adverse reactions in postmenopausal osteoporosis, back pain, pain in extremity, musculoskeletal pain, hypercholesterolemia and cystitis. Its warnings cover severe hypocalcemia, hypersensitivity, osteonecrosis of the jaw, atypical femoral fractures, multiple vertebral fractures after discontinuation, serious infections and dermatologic reactions. This list is not complete; the full prescribing information governs.


Precautions

  • The reference label lists pre-existing hypocalcemia, pregnancy and hypersensitivity to the product as contraindications.
  • The label describes correcting hypocalcemia before treatment and monitoring calcium, as determined by the treating physician.
  • The label warns of multiple vertebral fractures following discontinuation of treatment.
  • The label advises a routine oral examination and attention to dental hygiene because of osteonecrosis of the jaw.

All use should follow the approved prescribing information and the instructions of the treating physician.


Storage and Handling

Please follow the storage instructions printed on the Denaxa carton and leaflet. For reference, the US Prolia label describes refrigeration at 2°C to 8°C in the original carton, protected from light, and states not to freeze. Keep out of reach of children.


Manufacturer Information

Denaxa is marketed by Abbott. A.K. Pharma is a licensed distributor and does not manufacture the product. As one of the pharmaceutical distributors serving Indian hospitals, we source Denaxa through authorised channels and supply it with pack and batch details. Buyers comparing a pharmaceutical wholesale distributors list or a pharma distribution company can verify our credentials on the About Us page.


Related Medicines


Frequently Asked Questions

Is Denaxa available in India?
A.K. Pharma supplies Denaxa (denosumab) Denosumab 60 mg/mL prefilled syringe to hospitals and pharmacies in India. Contact us for current availability.

What does Denaxa contain?
Denosumab 60 mg/mL, a RANKL-inhibitor monoclonal antibody supplied as a single-dose prefilled syringe.

Can I order a single pack?
A.K. Pharma is a distributor and supplies bulk/wholesale quantities only, not one or two pieces.

How should Denaxa be stored?
Follow the carton; the US reference label describes 2°C to 8°C in the original carton, not frozen.

Does A.K. Pharma advise on dosing or suitability?
No. Treatment decisions, including dosing, rest solely with the treating physician and the approved prescribing information.

How do I request a quote?
Call or WhatsApp us, or use the contact details below.


Why Order from A.K. Pharma

  • Licensed pharmaceutical distributor in Delhi with 25+ years in specialty medicines
  • Genuine, original-pack stock
  • Bulk/wholesale supply to hospitals and pharmacies
  • Batch and expiry details on request
  • Dedicated team for hospital procurement queries

Sources and Further Reading


Contact A.K. Pharma for Denaxa Supply

📍 E-2/257A, 2nd Floor, Shastri Nagar, New Delhi 110052
📞 011 4172 6999
📱 WhatsApp: +91 9810034827
🌐 akpharma.in


Disclaimer: This page is intended for informational and sourcing/procurement purposes only and does not constitute medical or clinical advice. A.K. Pharma is a licensed medicine distributor, not a healthcare provider, and does not provide clinical guidance. All treatment decisions, including drug selection and dosing, rest solely with the treating physician and should follow the approved prescribing information.

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