Lucrin Depot® (Leuprolide Acetate)

Lucrin Depot® (Leuprolide Acetate) Leuprolide acetate 3.75 mg and Leuprolide acetate 11.25 mg depot injection by Abbott. Genuine stock supplied in bulk/wholesale quantities to hospitals and pharmacies across India by A.K. Pharma, a licensed pharmaceutical distributor in Delhi.

Additional information

Composition

Leuprolide acetate 3.75 mg / Leuprolide acetate 11.25 mg

Manufacturer

Abbott

Country

EU

Pack size

Leuprolide acetate 3.75 mg: 1 vial / carton; Leuprolide acetate 11.25 mg: 1 vial + 1 diluent ampoule / carton

Storage

As per carton and leaflet; original pack

Prescription medicine

Supplied only against a valid prescription from a registered medical practitioner.

100% genuine

Sourced from authorised channels

Cold-chain delivery

Temperature-controlled packing

Pan-India delivery

Hospitals, clinics, pharmacies

Licensed distributor

Delhi drug licence holder

Product information

Lucrin Depot® (Leuprolide Acetate) Leuprolide acetate 3.75 mg and Leuprolide acetate 11.25 mg Depot Injection — GnRH Agonist Depot Suspension: A Sourcing Guide for Hospitals and Oncology Pharmacies

Lucrin Depot® is a brand of leuprolide acetate for depot suspension, a gonadotropin-releasing hormone (GnRH) agonist, marketed by Abbott. According to the US prescribing information for the same active ingredient and depot formulation (Lupron Depot®), the 22.5 mg strength is indicated for advanced prostate cancer, while the 3.75 mg and 11.25 mg strengths are indicated for endometriosis and for uterine fibroids with iron therapy. Indications for Lucrin Depot in India are defined by its approved pack insert and the Indian regulator. The decision to prescribe leuprolide acetate, including patient selection, dose and monitoring, rests entirely with the treating physician. This page provides sourcing and procurement information for hospitals and pharmacies, not clinical or treatment guidance.

As both a trusted medicine distributor in Delhi and a licensed pharmaceutical distributor in Delhi, A.K. Pharma supplies genuine Lucrin Depot® (leuprolide acetate) Leuprolide acetate 3.75 mg and Leuprolide acetate 11.25 mg depot injection to hospitals, oncology centres and pharmacies across India. Buyers comparing pharmaceutical distribution companies and wholesale pharmaceutical distributors can also browse our full product range and the cancer medicines category. Supply is in bulk/wholesale quantities only.


What is Lucrin Depot (Leuprolide Acetate)?

Lucrin Depot contains leuprolide acetate, a synthetic GnRH agonist supplied as a lyophilised depot powder with a diluent, given as an injection by a healthcare provider. The Lucrin Depot cartons list 3.75 mg and 11.25 mg strengths.

How it works, according to the label: The reference label describes leuprolide acetate as a GnRH agonist. Given continuously, it suppresses pituitary gonadotropins, which lowers sex-hormone levels. The label also notes a temporary rise in testosterone (tumor flare) in the first weeks of treatment in prostate cancer.


Indications as Listed in the Reference Label

The current US prescribing information for undefined (DailyMed) lists the following. Indications in India may differ and are defined by the Indian regulator and the Lucrin Depot pack insert.

  • Lupron Depot 22.5 mg (3-month) and the other prostate-cancer strengths: treatment of advanced prostate cancer
  • Lupron Depot 3.75 mg (1-month) and 11.25 mg (3-month): management of endometriosis, including pain relief and reduction of endometriotic lesions
  • Lupron Depot 3.75 mg and 11.25 mg: use with iron therapy for preoperative hematologic improvement of women with anemia caused by uterine fibroids
  • The endometriosis labels state a limit on total duration of therapy (not more than 12 months with add-back therapy) because of concerns about bone mineral density
  • Central precocious puberty in children is covered by a separate label (Lupron Depot-PED)

Clinical Studies and Evidence

The Lupron Depot labels summarise controlled studies in which 3.75 mg given monthly for six months was comparable to danazol in relieving clinical signs and symptoms of endometriosis, and open-label studies in advanced prostate cancer that measured suppression of serum testosterone to castrate range. The 22.5 mg label reports castrate-range suppression within 30 days in 87 of 92 patients. Full results are in the DailyMed prescribing information. Evidence is cited for information only and is not a recommendation for any patient; the approved prescribing information governs.


Available Strengths and Packs

Strength Dosage form Pack size (as shown on the carton)
Leuprolide acetate 3.75 mg Depot injection (lyophilised powder with diluent) 1 vial / carton
Leuprolide acetate 11.25 mg Depot injection (lyophilised powder with diluent) 1 vial + 1 diluent ampoule / carton

Please confirm the current pack and batch with us before ordering. Dose and regimen must be determined and followed exactly as directed by the treating physician and the approved prescribing information.


Key Benefits for Procurement

  • Genuine, sealed original-pack stock sourced through authorised channels
  • Multiple strengths of one brand available from a single source
  • Batch and expiry details provided on request
  • Careful handling and storage of stock before dispatch
  • Documentation support for hospital purchase departments

Who Is This Page For?

This page is written for hospital pharmacists, oncology, urology and gynaecology department buyers, and pharmacies that source specialty hormonal injections. Leuprolide acetate depot is administered by a healthcare provider, as described in the prescribing information.


Possible Side Effects Reported in the Label

The Lupron Depot labels list warnings including tumor flare in prostate cancer (a temporary rise in testosterone in the first weeks), metabolic changes such as hyperglycemia, diabetes and hyperlipidemia, increased cardiovascular risk (myocardial infarction, sudden cardiac death, stroke), loss of bone mineral density with the endometriosis strengths, severe cutaneous adverse reactions, and embryo-fetal toxicity. This list is not complete; the full prescribing information governs.


Precautions

  • The label lists hypersensitivity to GnRH, GnRH agonists or any excipient as a contraindication.
  • The 3.75 mg and 11.25 mg labels state that the two strengths have different release characteristics and are dosed differently, and must not be substituted for each other.
  • The label states the product may cause fetal harm and describes the need to exclude pregnancy, as determined by the treating physician.
  • The label describes monitoring for metabolic and bone-density changes, as determined by the treating physician.
  • All use should follow the approved prescribing information and the instructions of the treating physician.

All use should follow the approved prescribing information and the instructions of the treating physician.


Storage and Handling

Please follow the storage instructions printed on the Lucrin Depot carton and leaflet. For reference, the US Lupron Depot labels describe storage at controlled room temperature, 20°C to 25°C. Keep in the original pack, out of reach of children.


Manufacturer Information

Lucrin Depot is marketed by Abbott. A.K. Pharma is a licensed distributor and does not manufacture the product. As one of the pharmaceutical distributors serving Indian hospitals, we source Lucrin Depot through authorised channels and supply it with pack and batch details. Buyers comparing a pharmaceutical wholesale distributors list or a pharma distribution company can verify our credentials on the About Us page.


Related Medicines


Frequently Asked Questions

Is Lucrin Depot available in India?
A.K. Pharma supplies Lucrin Depot (leuprolide acetate) Leuprolide acetate 3.75 mg and Leuprolide acetate 11.25 mg depot injection to hospitals and pharmacies in India. Contact us for current availability.

What does Lucrin Depot contain?
Leuprolide acetate, a GnRH agonist, as a depot (extended-release) injection in 3.75 mg and 11.25 mg strengths.

Can I order a single pack?
A.K. Pharma is a distributor and supplies bulk/wholesale quantities only, not one or two pieces.

How should Lucrin Depot be stored?
As printed on the carton and leaflet, in the original pack. The US Lupron Depot label describes controlled room temperature.

Does A.K. Pharma advise on dosing or suitability?
No. Treatment decisions, including dosing, rest solely with the treating physician and the approved prescribing information.

How do I request a quote?
Call or WhatsApp us, or use the contact details below.


Why Order from A.K. Pharma

  • Licensed pharmaceutical distributor in Delhi with 25+ years in specialty medicines
  • Genuine, original-pack stock
  • Bulk/wholesale supply to hospitals, oncology centres and pharmacies
  • Batch and expiry details on request
  • Dedicated team for hospital procurement queries

Sources and Further Reading


Contact A.K. Pharma for Lucrin Depot Supply

📍 E-2/257A, 2nd Floor, Shastri Nagar, New Delhi 110052
📞 011 4172 6999
📱 WhatsApp: +91 9810034827
🌐 akpharma.in


Disclaimer: This page is intended for informational and sourcing/procurement purposes only and does not constitute medical or clinical advice. A.K. Pharma is a licensed medicine distributor, not a healthcare provider, and does not provide clinical guidance. All treatment decisions, including drug selection and dosing, rest solely with the treating physician and should follow the approved prescribing information.

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